Technology Insight: water diffusion MRI—a potential new biomarker of response to cancer therapy
Daniel M Patterson, Anwar R Padhani* and David J Collins
Correspondence *Paul Strickland Scanner Centre, Mount Vernon Hospital, Rickmansworth Road, Northwood, Middlesex HA6 2RN, UK
Email anwar.padhani@stricklandscanner.org.uk
Preclinical and clinical data indicate a number of potential roles of diffusion-weighted MRI in the characterization of malignancy such as determination of lesion aggressiveness and monitoring response to therapy. This Review outlines the biological basis of observations made using this technique and the authors discuss the strength of evidence for adoption of DW-MRI as a biomarker for the assessment of tumor response.
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