Cyclo-oxygenase 2 expression correlates with poor prognosis in breast cancer
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There is evidence to indicate that cyclo-oxygenase 2 (COX2) might promote tumor growth and spread by stimulating angiogenesis and inhibiting apoptosis; however studies examining the association between COX2 expression and prognosis have produced conflicting results. A study by Zerkowski and colleagues has now demonstrated a relationship between high COX2 expression and poor outcome in breast cancer.
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