Research Highlights

Nature Clinical Practice Oncology (2007) 4, 331-332
doi:10.1038/ncponc0807  

Basal subtype breast carcinomas express EGFR and might be candidates for targeted therapy

This article has no abstract so we have provided the first paragraph of the full text.

The recent discovery that the different types of breast carcinoma have distinctive gene expression signatures has enabled tumor subtypes to be easily identified by immunohistochemical profiling techniques. Breast carcinoma subtypes are associated with different clinical outcomes, and targeted therapies might be appropriate in some cases. Here, Siziopikou and Cobleigh suggest that the basal subtype of breast carcinomas might be a candidate for therapies targeted against EGFR.

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