Poor results with intensified maintenance chemotherapy in acute promyelocytic leukemia
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A prospective, multicenter study by the Japan Adult Leukemia Study Group, JALSG APL97, has shown that moderately intensive intermittent maintenance chemotherapy is detrimental to the survival of patients with acute promyelocytic leukemia (APL) who have become negative for the PML-RAR
transcript after intensive consolidation chemotherapy.
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