Resistant subclone expansion is associated with relapse in pediatric patients with ALL
This article has no abstract so we have provided the first paragraph of the full text.
Relapse is a major challenge in the successful treatment of acute lymphoblastic leukemia (ALL); approximately 20% of children diagnosed with ALL will eventually relapse and become highly resistant to further therapy. Choi et al. have investigated the mechanisms of ALL relapse, using polymerase chain reaction analyses to assess antigen-receptor gene rearrangements in children with ALL.
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