Association between radiation-induced xerostomia and QOL in head and neck cancer
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Xerostomia is the most frequently reported late side effect of radiation for the treatment of head and neck cancer. Uncertainty regarding the clinical relevance of radiation-induced xerostomia in relation to patient quality of life (QOL) led Jellema et al. to test the following two hypotheses: firstly, that higher grades of radiation-induced toxicity correlate with worse QOL; and secondly, that the impact of radiation-induced xerostomia on overall QOL lessens with time.
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