FIGURE 1  Pathophysiology of anemia

From the following article:

Cancer-related anemia and recombinant human erythropoietin—an updated overview

Julia Bohlius, Olaf Weingart, Sven Trelle and Andreas Engert

Nature Clinical Practice Oncology (2006) 3, 152-164
doi:10.1038/ncponc0451

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Figure 1.  Pathophysiology of anemia

BFU-E, erythropoietic burst formation; CFU-E, erythrocytic colony formation; EPO, erythropoietin; HIF-1, hypoxia-inducible factor-1; IFN-alpha,beta, interferon-alpha,beta; IFN-gamma, interferon-gamma; IL-1, interleukin-1; TNF, tumor-necrosis factor. Figure modified with permission from reference 86 © (1996) Marcel Dekker).

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