RON and MET co-expressionis a prognostic indicator in bladder cancer patients
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Protein tyrosine kinases are vital to many cell regulatory processes. The majority of known PROTO-ONCOGENES expressed in solid tumors encode protein tyrosine kinases. Understanding their expression patterns could aid cancer prognosis and treatment. Cheng and co-workers have found a link between decreased survival in bladder cancer patients and expression of the receptor tyrosine kinase RON, the c-met protein (MET), or both.
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