Women with raised CRP levels are not at increased risk of colorectal cancer
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A reduced risk for development of some cancers has been associated with use of anti-inflammatory agents, and an increased risk has been associated with inflammatory bowel diseases. It has therefore been suggested that C-reactive protein (CRP, a marker of inflammation) might play a role in development of colorectal cancer. The mechanisms underlying this association are still unclear, and it is uncertain whether the inflammation is the cause or an effect of cancer. This 10-year, prospective, randomized, placebo-controlled study of the risks and benefits of vitamin E supplementation and low-dose aspirin, evaluated the prognostic value of CRP levels in determining risk of colorectal cancer in women.
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