Therapy Insight: potential of statins for cancer chemoprevention and therapy
Matthew S Katz
Correspondence Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Email mskatz@partners.org
Statins are commonly prescribed to treat dyslipidemia and to prevent coronary artery disease, but studies also indicate their potential for cancer prevention. Preclinical data suggest pleiotropic antineoplastic effects of statins, but clinical data assessing cancer risk associated with statin use are conflicting. This review critically discusses the existing evidence highlighting the role of statins for cancer chemoprevention.
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