P-glycoprotein expression predicts response to NACT in breast cancer
Carol Lovegrove
This article has no abstract so we have provided the first paragraph of the full text.
Neoadjuvant chemotherapy (NACT) is an important aspect of the management of locally advanced breast cancer, but chemoresistance can limit efficacy. The ability to predict response would allow patient-specific tailoring of treatment regimens and possibly allow the avoidance of toxicity associated with ineffective chemotherapy.
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