Decreased dissemination and increased transgene expression using novel viral gene delivery
Carol Lovegrove
This article has no abstract so we have provided the first paragraph of the full text.
Intratumor injection of viral vectors is the most commonly used system for gene delivery in clinical trials of cancer therapies. Dissemination from the targeted tumor into the surrounding tissues remains a potential problem, however, and can result in reduced efficacy: toxicity ratios.
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