Mechanisms of Disease: prediction and prevention of breast cancer—cellular and molecular interactions
Anthony Howell*, Andrew H Sims, Kai Ren Ong, Michelle N Harvie, D Gareth R Evans and Robert B Clarke
Correspondence *CR-UK Dept of Medical Oncology, University of Manchester, Christie Hospital (NHS) Trust, Wilmslow Road, Withington, Manchester M20 4BX, UK
Email maria.parker@christie-tr.nwest.nhs.uk
Breast cancer is a multifactorial condition, and changes in cellular biology are affected by a large number of variables known to affect an individual's susceptibility to this malignancy. Current risk prediction models are based on combinations of risk factors and have good predictive but low discriminatory power. Risk estimation might be improved by incorporating additional factors into risk prediction models, which will allow better determination of breast cancer risk and provide new targets for preventive therapies.
Full text of this article is available with one of the following:
- Personal subscription Purchase your own personal subscription to this journal. Already a subscriber? Please log in for immediate access.
- 7 day single article pass for US$32 In order to purchase this article you must be a registered user. Please register or log in.
- Site licence Learn more about institutional site licences
Current Subscribers
Please log in to access the full text article using the login box at the top of the page.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
In vivo imaging reveals estrogen receptor's hidden personalityNature Medicine News and Views (01 Jan 2003)
Breast cancer biology blossoms in the clinicNature Medicine News and Views (01 Jul 1998)