The UbcH10 gene is a novel therapeutic target in anaplastic thyroid carcinoma
Alexandra King
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The discovery of a 150-fold upregulation of the UbcH10 gene in human thyroid carcinoma cell lines of varying histotype was the focus of a recent analysis by Pallante et al., published in the British Journal of Cancer. The group investigated the role of UbcH10 in thyroid carcinogenesis and proposed that the UbcH10 protein might represent a novel tumor marker and a therapeutic target in anaplastic thyroid carcinoma.
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