Liver transplantation or resection for hilar cholangiocarcinoma?

Katy Cherry

This article has no abstract so we have provided the first paragraph of the full text.

Therapy for hilar cholangiocarcinoma (CCA) remains a challenge. Curative resection is often not an option owing to vascular encasement, hilar invasion, bilateral liver involvement and primary sclerosing cholangitis; however, to date, liver transplantation has achieved limited long-term survival in the majority of patients. Rea and colleagues have designed a protocol of neoadjuvant chemoradiotherapy and orthotopic liver transplantation for patients with unresectable hilar CCA, and compared survival and recurrence rates with patients treated with conventional resection.

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