Editor-in-Chief: Vincent T DeVita Jr, MD

Nature Clinical Practice Oncology delivers timely interpretations of key research developments, translating the latest findings into clinical practice. Our Editor-in-Chief and international Advisory Board ensure comprehensive coverage of topical issues throughout the year, with the highest standards of editorial quality and integrity that are hallmarks of Nature Publishing Group.

Table of Contents: March 2009

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Featured Article 1

Pharmacogenomic progress in individualized dosing of key drugs for cancer patients

Christine M Walko and Howard McLeod

Determining the correct dosage for the majority of chemotherapeutic agents presents a challenge for clinicians because there is a fine balance between doses that cause significant drug toxicity and loss of efficacy. This Review discusses the current limitations of body surface area-based dosing, provides examples of successful pharmacogenomics investigations that have used drug-metabolizing enzymes to decrease drug toxicity or improve efficacy, and highlights promising advances in pharmacogenomic-directed pharmacotherapy.

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Featured Article 2

Unintended pregnancy during radiotherapy for cancer

Saskia N de Wildt, Nobuko Taguchi and Gideon Koren

Women with cancer treated with radiotherapy who become pregnant have an increased risk of poor fetal outcome. The case of a 27-year-old woman who became pregnant while receiving radiotherapy for Hodgkin lymphoma, and gave birth to a healthy infant is described. The authors suggest that careful evaluation of fetal exposure to radiation should be performed in each individual case to allow pregnant patients to decide on the fate of their pregnancy.

ESO e-grandround

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The European School of Oncology (ESO) in partnership with Nature Clinical Practice Oncology is pleased to announce the 41st e-grandround, entitled "Optimizing approaches to head and neck cancer. Metastatic head and neck cancer? New options". This topic will be discussed by Dr Lisa Licitra during a live webcast on Thursday 26 March 17:15–18:00 UK time. Online participants will be able to submit questions.

Please visit www.e-eso.net for further information.

Advance Online Publication

Advance Online Publication

We believe that rapid online publication is a valuable service to readers and we now include an Advance Online Publication (AOP) table of contents on our website. AOP articles are uploaded each week and are listed in order of publication date (beginning with the most recent). Each article carries a digital object identifier (doi), which is a unique electronic identification tag for that article. As soon as the monthly issue is printed, articles are removed from the AOP table of contents, assigned a page number and transferred to that issue's table of contents on the website. We encourage you to visit the AOP table of contents.

Forthcoming articles

Don't miss the following articles that will soon be appearing in the pages of Nature Clinical Practice Oncology!

Forthcoming articles

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Full text content of the January 2009 issue is freely available in both HTML and PDF formats.

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