Viewpoint

Nature Clinical Practice Neurology (2008) 4, 236-237
doi:10.1038/ncpneuro0774  
Received 6 November 2007 | Accepted 18 February 2008 | Published online: 25 March 2008

Immunotherapy for clinically isolated syndrome? Not necessarily...

Aksel Siva

Correspondence Department of Neurology, Istanbul University Cerrahpas cedila School of Medicine Cerrahpas cedila, 34098 Istanbul, Turkey

Email
 asiva@turk.net

Multiple sclerosis (MS) is a complex disease with a high degree of clinical and neuropathological variability between patients. In this Viewpoint, Aksel Siva argues that such a heterogeneous disease demands a heterogeneous approach to treatment and questions the practice of initiating long-term immunotherapy before the MS diagnosis has become definite.

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