Fly model provides new insights into Huntington's disease pathogenesis
This article has no abstract so we have provided the first paragraph of the full text.
Expansion of a CAG repeat in the Huntingtin (htt) protein causes the neurodegenerative disorder Huntington's disease (HD). In a recent study, Romero et al. used a Drosophila model of HD that expressed the entire human htt protein with a 128 glutamine expansion (128QhttFL) to investigate the role of the expanded protein in the disorder.
Full text of this article is available with one of the following:
- Personal subscription Purchase your own personal subscription to this journal. Already a subscriber? Please log in for immediate access.
- 7 day single article pass for US$18 In order to purchase this article you must be a registered user. Please register or log in.
- Site licence Learn more about institutional site licences
Current Subscribers
Please log in to access the full text article using the login box at the top of the page.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Huntington's disease Genetics lends a handNature News and Views (12 Jun 2008)
Polyglutamines, nuclear inclusions and neurodegenerationNature Medicine News and Views (01 Nov 1997)
Polyglutamine neurodegeneration: minding your Ps and QsNature Medicine News and Views (01 Jul 2003)
Normal and mutant huntingtin: Partners in crime?Nature Medicine News and Views (01 Nov 2000)
How trinucleotide repeats may functionNature News and Views (09 Nov 1995)
See all 7 matches for News And Views