Prevalence of silent brain infarction in obstructive sleep apnea
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Patients with obstructive sleep apnea (OSA) exhibit high levels of cerebrovascular mortality and morbidity. Cerebrovascular events in OSA are often preceded by silent brain infarction (SBI); however, the relationship between OSA and SBI has not been clearly defined, and the results of previous studies have been confounded by comorbidities. To address these issues, Minoguchi et al. have evaluated the prevalence of SBI, and of systemic inflammation and platelet activation, in 50 male patients with OSA and in 15 age-matched obese controls.
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