Molecular imaging of brain amyloid in mild cognitive impairment and Alzheimer's disease

Paul M Matthews

This article has no abstract so we have provided the first paragraph of the full text.

A proportion of people with the recently defined syndrome of MCI are at high risk of developing AD over the short term, with about 12% of those with the amnestic form of MCI showing progression to AD each year.¹ The current study demonstrates that PET using the -amyloid-binding radioligand FDDNP can distinguish people with MCI from patients with AD on the basis of brain amyloid load. It indicates that the transition from MCI to AD is associated with brain amyloid accumulation.

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