Perfusion-weighted MRI predicts cerebral hyperperfusion after carotid endarterectomy
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A small subset of patients who undergo carotid endarterectomy (CEA) develop cerebral hyperperfusion syndrome, a serious complication with a poor prognosis. In a recent study, Fukuda et al. have investigated whether the quantitative measurement of preoperative cerebral blood volume (CBV) by perfusion-weighted MRI could be used to predict post-CEA cerebral hyperperfusion in patients with unilateral internal carotid artery stenosis. Hyperperfusion was assessed by CT, and was defined as an at least twofold increase in ipsilateral cerebral blood flow (CBF) relative to preoperative measurements.
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