Repetitive nerve stimulation is a clinically useful test for cramp–fasciculation syndrome
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Cramp–fasciculation syndrome (CFS) has been suggested to be caused by hyperexcitability of peripheral nerves. Reasons for this hypothesis include an overlap in symptomatology of CFS and acquired neuromyotonia, and the fact that afterdischarges and cramp potentials following repetitive nerve stimulation (RNS) occur more readily in patients with CFS than in individuals without this condition. Conclusive evidence for this hypothesis, however, is lacking.
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