Viewpoint

Nature Clinical Practice Neurology (2007) 3, 590-591
doi:10.1038/ncpneuro0618  
Received 11 May 2007 | Accepted 31 July 2007 | Published online: 18 September 2007

Publication bias against negative results from clinical trials: three of the seven deadly sins

Richard T Johnson* and Kay Dickersin

Correspondence *The Johns Hopkins Hospital, Pathology 627, Baltimore, MD 21287, USA

Email
 rtj@jhmi.edu

There is strong evidence that clinical trials with a positive outcome are more likely to be published than are trials with negative results. In this Viewpoint, Richard Johnson and Kay Dickersin explore the reasons for this phenomenon and discuss possible solutions.

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