Metabolic condition of brain tissue after ischemic stroke identifies the penumbra
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After acute ischemic stroke, accurate identification of the penumbra is critical to ensure that potentially dangerous thrombolytic treatment is directed only at salvageable tissue. Current MRI methods such as perfusion–diffusion mismatch can lead to an overestimation of the final lesion volume, and a recent study in Germany investigated whether measurement of the metabolic condition of brain tissue using blood-oxygen-level-dependent (BOLD) MRI could improve penumbra identification.
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