Table of contents
July 2006 Volume 2 No 7
Editorial
Viewpoint
How can teleneurology improve patient care?
346Telemedicine has the potential to improve access, efficiency and quality of health care. In this Viewpoint, Victor Patterson and Richard Wootton explore how telemedicine might change the face of neurological practice.
Research Highlights
The role of gp120 in the HIV-associated sensory neuropathies
348Enhancement of neuroprotective activity by deactivation of a blood–brain transporter
348Photosensitivity in patients with epilepsy can be controlled using a blue lens
348Mutations in COL4A1 might increase risk of hemorrhagic stroke
349Transcranial direct current stimulation controls pain in traumatic spinal cord injury
349Special education data cannot substantiate claims of an autism epidemic
350Transcutaneous electrical stimulation for pain assessment
350Does long-term antihypertensive treatment affect risk of dementia?
351Low-frequency ultrasound causes brain edema and intracerebral necrosis in rats
351Epstein–Barr virus levels elevated up to 20 years before onset of multiple sclerosis
351New tool to alert clinicians to nonmotor symptoms in Parkinson's disease
352Strong support for partial integration of neurology and psychiatry teaching
352New role for MMP-9 in neurovascular remodeling after stroke
353Practice Points
Should stroke patients with mild or improving symptoms receive tissue plasminogen activator therapy?
354How beneficial is noninvasive ventilation in patients with amyotrophic lateral sclerosis?
356Can we avoid misdiagnosis of epilepsy by discriminating between wicket rhythms and epileptiform activity?
358Is a combination of tramadol and acetaminophen effective for the treatment of acute migraine pain?
360Are young people with an elevated carotid intima–media thickness at increased risk of vascular events?
362Reviews
Diagnosing carpal tunnel syndrome—clinical criteria and ancillary tests
366Carpal tunnel syndrome results from damage to the median nerve at the wrist, and is associated with a range of symptoms, including pain and numbness in the hand. In this review, the authors describe the clinical criteria that are used by clinicians to reach a diagnosis of carpal tunnel syndrome, and discuss how the diagnosis can be supported by ancillary tests, such as nerve conduction studies and imaging.
doi:10.1038/ncpneuro0216 | Full Text | PDF (165K)
The diagnosis and treatment of idiopathic normal pressure hydrocephalus
375Idiopathic normal pressure hydrocephalus (INPH) is characterized by gait impairment, cognitive decline and urinary incontinence, and is associated with ventricular enlargement in the absence of elevated cerebrospinal fluid pressure. This review describes the diagnosis and treatment of INPH, with particular reference to the recently published INPH consensus guidelines.
doi:10.1038/ncpneuro0237 | Full Text | PDF (226K)
Drug Insight: continuous dopaminergic stimulation in the treatment of Parkinson's disease
382Chronic levodopa treatment in patients with Parkinson's disease frequently results in the development of motor complications, including dyskinesias and motor fluctuations. This review presents evidence that these complications are associated with discontinuous stimulation of dopamine receptors that is induced by intermittent oral doses of levodopa, and the authors propose alternative therapeutic approaches based on the principle of continuous dopaminergic stimulation.
doi:10.1038/ncpneuro0222 | Full Text | PDF (278K)
Case Study
Myotonia congenita—a cause of muscle weakness and stiffness
393doi:10.1038/ncpneuro0239 | Full Text | PDF (207K)
