Absence of Oxalobacter formigenes is associated with formation of kidney stones
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Oxalobacter formigenes is a Gram-negative, anaerobic bacterium that breaks down oxalate in the colon. Small studies have suggested that the absence of O. formigenes might result in increased urinary oxalate levels and, thus, lead to the formation of calcium oxalate kidney stones. Kaufman et al. have determined in a large population that lack of O. formigenes colonization is associated with an increased risk of kidney stone formation but not necessarily with urinary oxalate excretion.
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