Combining low-sodium diet and diuretic maximizes antiproteinuric efficacy of RAAS blockade
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A high sodium intake inhibits the renoprotective effect of blockade of the renin–angiotensin–aldosterone system (RAAS). Vogt et al. investigated the combined effects of a low-sodium diet and the diuretic hydrochlorothiazide on proteinuria and blood pressure in Dutch patients receiving the angiotensin-receptor blocker losartan.
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