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Nature Clinical Practice Nephrology (2008) 4, 293-294
doi:10.1038/ncpneph0815  

Nocturnal hemodialysis might improve fertility of women on renal replacement therapy

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In comparison with women in the general population, women on conventional hemodialysis have decreased fertility and a higher incidence of fetal mortality. Barua et al. have suggested that uremia-related changes might partially explain these poor outcomes. They hypothesize that by enhancing solute clearance, nocturnal hemodialysis could facilitate successful pregnancy in women on renal replacement therapy. In a recent paper, the group has reported the clinical outcomes of all women who delivered a live infant during the period 2001–2006 while on nocturnal hemodialysis in Toronto, ON, Canada.

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