Asymptomatic urinary tract infection is unlikely to cause proteinuria or microalbuminuria
Lindsay E Nicolle
Correspondence University of Manitoba, Health Sciences Centre, Room GG443–820, Sherbrook Street, Winnipeg, MB R3A 1R9, Canada
Email lnicolle@hsc.mb.ca
This article has no abstract so we have provided the first paragraph of the full text.
Characterization of the quantity and types of urine protein is a basic diagnostic test for identification and management of some renal diseases. Proteins in the urine can be derived from plasma (after filtration at the glomerular capillaries), renal tubules (through secretion or leakage following injury), or the lower urinary tract (through secretion or leakage as a result of tissue injury or inflammation). Glomerular proteinuria frequently occurs with systemic infections that are accompanied by fever. Tubular proteinuria occurs in renal diseases characterized by acute inflammation, including acute pyelonephritis. Proteinuria can, therefore, be attributable to systemic infection or to infections originating in either the upper or lower urinary tract. Screening patients to exclude the presence of UTI has been recommended before further evaluation of proteinuria is undertaken.1
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