Modulation of renal cell injury by heat shock proteins: lessons learned from the immature kidney
Michael Riordan, Rajasree Sreedharan, Michael Kashgarian and Norman J Siegel*
Correspondence *Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA
Email norman.siegel@yale.edu
In critical care units, acute renal failure is less common in premature infants than in more mature individuals. Recent studies indicate a role for the heat shock response in this clinical phenomenon. Distilled here, these new data could lead to strategies for identifying patients at greatest risk of developing acute renal failure.
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