Anion-gap interpretation: the old and the new
Michael Emmett
Correspondence Baylor University Medical Center, 3500 Gaston Avenue, Dallas, TX 7524, USA
Email m.emmett@baylorhealth.edu
The plasma concentration of sodium ions normally exceeds the sum of the plasma concentrations of chloride and bicarbonate ions. Calculation of the resulting 'anion gap' can aid the diagnosis of various acid–base and electrolyte disorders. Michael Emmett discusses the utility of this approach, and highlights the potential disrupting factors which should be taken into account when interpreting anion gap calculations.
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