Review

Nature Clinical Practice Nephrology (2005) 1, 22-32
doi:10.1038/ncpneph0021  
Received 17 May 2005 | Accepted 1 September 2005

Adult stem cells in the repair of the injured renal tubule

Lloyd G Cantley

Correspondence Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, CT 06520, USA

Email
 lloyd.cantley@yale.edu

Age-related decline in the capacity of the kidney to repair itself is a significant contributor to mortality associated with acute renal failure. In this well-balanced overview of renal and bone-marrow stem cells, Lloyd Cantley summarizes current knowledge and speculates on mechanisms of regeneration that have therapeutic potential.

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