Research Highlights

Nature Clinical Practice Gastroenterology & Hepatology (2004) 1, 67
doi:10.1038/ncpgasthep0047  

Avoiding false positives in H. pylori detection

This article has no abstract so we have provided the first paragraph of the full text.

The 13C-urea breath test (UBT) is widely used in the diagnosis of H. pylori infection. False-positive results can be generated, however, by other urease-producing bacteria in the mouth and intestine. Several methods have been devised to avoid this problem, including the endoscopic UBT, in which 13C-urea solution is sprayed directly into the stomach. Although this approach is more reliable, it is invasive and relatively inconvenient. Urita and colleagues have recently described a non-invasive modification, based on breath sample collection through the nostril.

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