Collections: celiac disease

celiac disease collection image

Welcome to the Nature Clinical Practice Gastroenterology & Hepatology celiac disease collection - a selection of Reviews, Viewpoints, Practice Points, Highlights, and Original Research that have been published on this topic in Nature Publishing Group journals since 2003. During October 2005, celiac disease awareness month in the US, the articles included in this collection are freely available.

Featured Article

Future therapeutic options for celiac disease

Ludvig M Sollid and Chaitan Khosla

Recent advances have improved our understanding of the molecular basis of celiac disease and new targets for rational therapy have been identified. This Review discusses concepts for new treatments and their current status.

Featured Article

How important is the timing of gluten introduction for children with celiac disease?

Afzal J Naiyer and Peter HR Green

This article puts into context the findings of a study by Norris et al., which demonstrated that protection from celiac disease was afforded when gluten was administered during the 4–6 month period after birth.

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Research Highlights

Celiac disease: timing of gluten introduction in the infant diet

Nature Clinical Practice Gastroenterology & Hepatology2, 294 (01 Jul 2005)

doi: 10.1038/ncpgasthep0203 | Full Text| PDF

Celiac disease: malignancy and mortality

Nature Clinical Practice Gastroenterology & Hepatology 1, 67 (01 Dec 2004)

doi: 10.1038/ncpgasthep0036 | Full Text| PDF

Gluten intolerance: inhibitors for human TGM2 enzyme

Nature Reviews Drug Discovery 2, 420 (01 Jun 2003)

doi: 10.1038/nrd1118 | Full Text|

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Viewpoint

Is a life-long gluten-free diet for patients with celiac disease successful?

Rachele Ciccocioppo and Gino Roberto Corazza

The ubiquity of gluten in foodstuffs, patient compliance, and variable patient susceptibility to gluten are all limiting factors of the gluten-free diet-the treatment of choice for celiac disease.

Nature Clinical Practice Gastroenterology & Hepatology 2, 290-291 (01 Jul 2005)

doi: 10.1038/ncpgasthep0212 | Full Text| PDF

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Practice point

How important is the timing of gluten introduction for children with celiac disease?

Afzal J Naiyer and Peter HR Green

Nature Clinical Practice Gastroenterology & Hepatology 2, 444-445 (01 Oct 2005)

doi: 10.1038/ncpgasthep0289 | Full Text| PDF

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Reviews

Future therapeutic options for celiac disease

Ludvig M Sollid and Chaitan Khosla

Nature Clinical Practice Gastroenterology & Hepatology 2, 140-147 (01 Mar 2005)

doi: 10.1038/ncpgasthep0111 | Full Text | PDF

Mechanisms of Disease: the role of intestinal barrier function in the pathogenesis of gastrointestinal autoimmune diseases

Alessio Fasano and Terez Shea-Donohue

Nature Clinical Practice Gastroenterology & Hepatology 2, 416-422 (01 Sep 2005)

doi: 10.1038/ncpgasthep0259 | Full Text | PDF

Celiac Disease: a model autoimmune disease with gene therapy applications

M Londei, S Quaratino and L Maiuri

Gene Therapy 10, 835-843 (01 May 2003)

doi: 10.1038/3302041a | Full Text | PDF

Celiac Disease: a progress report

Donald A. Antonioli

Modern Pathology 16, 342-346 (01 Apr 2003)

doi: 10.1038/3880771a | Full Text | PDF

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Research

A common CTLA4 haplotype associated with coeliac disease

Karen A Hunt, Dermot P B McGovern, Parveen J Kumar, Subrata Ghosh, Simon P L Travis, Julian R F Walters, Derek P Jewell, Raymond J Playford and David A van Heel

European Journal of Human Genetics 13, 440-444 (01 Apr 2005)

doi: 10.1038/3880771a | Full Text | PDF

Matrix metalloproteinase pattern in celiac duodenal mucosa

Rachele Ciccocioppo, Antonio Di Sabatino, Michael Bauer, Daniela N Della Riccia, Francesca Bizzini, Federico Biagi, Maria G Cifone, Gino R Corazza and Detlef Schuppan

Laboratory Investigation 85, 397-407 (01 Mar 2005)

doi: 10.1038/3700225a | Full Text | PDF

A functional variant of IFNγ gene is associated with coeliac disease

B Rueda, A Martínez, M A López-Nevot, A Mas-Fontao, L Paco, E Ortega, M Fernández-Arquero, E Urcelay, E Gomez de la Concha and J Martín

Genes and Immunity 5, 517-519 (01 Sep 2004)

doi: 10.1038/3700225a | Full Text | PDF

CTLA4+49 A/G and CT60 polymorphisms in Dutch coeliac disease patient

Martine J van Belzen, Chris J J Mulder, Alexandra Zhernakova, Peter L Pearson, Roderick H J Houwen and Cisca Wijmenga

European Journal of Human Genetics 12, 782-785 (01 Sep 2004)

doi: 10.1038/5201165a | Full Text | PDF

Defining the contribution of the HLA region to cis DQ2-positive coeliac disease patients

M J van Belzen, B P C Koeleman, J B A Crusius, J W R Meijer, A F J Bardoel, P L Pearson, L A Sandkuijl, R H J Houwen and C Wijmenga

Genes and Immunity 5, 215-220 (01 May 2004)

doi: 10.1038/6364061a | Full Text | PDF

Genetic association of coeliac disease susceptibility to polymorphisms in the ICOS gene on chromosome 2q33

K Haimila, T Smedberg, K Mustalahti, M Mäki, J Partanen and P Holopainen

Genes and Immunity 5, 85-92 (01 Mar 2004)

doi: 10.1038/6364040a | Full Text | PDF

Meta and pooled analysis of European coeliac disease data

Marie-Claude Babron, Staffan Nilsson, Svetlana Adamovic, Åsa Torinsson Naluai, Jan Wahlström, Henry Ascher, Paul J Ciclitira, Ludvig M Sollid, Jukka Partanen, Luigi Greco, Francoise Clerget-Darpoux1 and the European Genetics Cluster on Coeliac Disease

European Journal of Human Genetics 11, 828-834 (01 Nov 2003)

doi: 10.1038/5201051a | Full Text | PDF

Adult coeliac patients do tolerate large amounts of oats

S Størsrud, M Olsson, R Arvidsson Lenner, L Å Nilsson, O Nilsson and A Kilander

European Journal of Clinical Nutrition 57, 163-169 (01 Jan 2003)

doi: 10.1038/1601525a | Full Text | PDF

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