Increasing TSH levels correlate with increasing risk of DTC
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High TSH levels are known to induce thyroid hypertrophy. To determine the role of TSH in the development of thyroid cancer, Haymart et al. conducted a retrospective cohort study to examine the association between preoperative TSH levels and differentiated thyroid cancer (DTC). They analyzed data from 843 patients who underwent thyroid surgery at a single center between 1994 and 2007 and for whom preoperative TSH levels and a histopathological diagnosis of DTC or benign thyroid disease were recorded.
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