Increased liver fat content in patients with type 2 diabetes is independent of obesity
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Many patients with type 2 diabetes have increased liver fat content, giving a high prevalence of nonalcoholic fatty liver disease; whether this increase is independent of obesity has not been confirmed. Kotronen and colleagues assessed liver fat content in patients with type 2 diabetes compared with that in nondiabetic individuals matched for age, sex and BMI. Since a simple measure of liver fat content in patients with type 2 diabetes would also be useful for directing therapy, the authors also measured glycemic markers, lipids, and liver enzyme concentrations in serum.
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