Is hypopituitarism predictable after traumatic brain injury?
Aaron Liew and Chris J Thompson*
Correspondence *Department of Endocrinology, Beaumont Hospital, Beaumont Road, Dublin 9, Ireland
Email christhompson@beaumont.ie
This article has no abstract so we have provided the first paragraph of the full text.
Hypopituitarism is now recognised as a common complication of acute TBI, with several studies showing that anterior pituitary hormone deficiency occurs in 20–50% of survivors of TBI.1, 2, 3 Although this concept is widely accepted, universal screening for hormone deficiency could overwhelm existing endocrine services. Development of guidelines that prioritize patients at high risk for post-TBI hypopituitarism is an important requirement.4 Most studies to date, however, have failed to show an association between severity of head injury, pattern of radiographic injury or neurosurgical intervention, and the risk of permanent hypopituitarism.
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