Review

Nature Clinical Practice Cardiovascular Medicine (2008) 5, 280-288
doi:10.1038/ncpcardio1163  
Received 21 March 2006 | Accepted 11 January 2008 | Published online: 11 March 2008

Measurement of carotid intima–media thickness to assess progression and regression of atherosclerosis

Eric de Groot*, Sander I van Leuven, Raphaël Duivenvoorden, Marijn C Meuwese, Fatima Akdim, Michiel L Bots and John JP Kastelein

Correspondence *Department of Vascular Medicine, Academic Medical Centre, Room F4-159-2, Meibergdreef 9, PO Box 22700, 1100 DE Amsterdam, The Netherlands

Email
 ericdegroot@amc.uva.nl

Atherosclerosis can remain below the clinical horizon for a long time. Acute vascular disease, however, can manifest clinically at almost any stage. Brightness ultrasonographic imaging of the carotid arterial walls can depict all stages of atherosclerotic arterial wall changes as a continuous variable. Here de Groot et al. describe the role of carotid IMT measurements as a tool in risk evaluation of individuals and explore how this technique could advance atherosclerosis research.

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