Low initial dose of aspirin is superior to a high dose after acute STEMI
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Immediate administration of aspirin after ST-segment-elevation myocardial infarction (STEMI) reduces the risk of vascular events, but the optimum dose in this setting is unknown. Berger et al. retrospectively analyzed data from two trials of fibrinolytic therapy in STEMI to determine the effect of high-dose versus low-dose aspirin on cardiovascular outcome and bleeding events.
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