Review

Nature Clinical Practice Cardiovascular Medicine (2008) 5, 208-218
doi:10.1038/ncpcardio1127  
Received 2 August 2007 | Accepted 14 December 2007 | Published online: 19 February 2008

Mechanisms of Disease: detrimental adrenergic signaling in acute decompensated heart failure

David S Feldman*, Terry S Elton, Benjamin Sun, Mickey M Martin and Mark T Ziolo

Correspondence *Davis Heart and Lung Research Institute, 473 West 12th Avenue, Columbus, OH 43210, USA

Email
 david.feldman@osumc.edu

Little is known about the basic pathologic mechanisms in acute decompensated heart failure (ADHF), despite ADHF being a large clinical problem. Here, David Feldman, Terry Elton, Benjamin Sun, Mickey Martin and Mark Ziolo focus on beta-adrenergic receptor signaling as one of the final common pathways that could directly contribute to ADHF.

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