Biomarker study validates link between trans fat consumption and coronary heart disease risk
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Many dietary assessment studies have demonstrated an association between a diet high in trans fat and an increased risk of coronary heart disease (CHD); however, these studies might not accurately reflect the relationship between trans fat intake and risk of CHD because of measurement errors associated with dietary assessment. Biomarkers have the advantage of being free of such errors. Sun et al., therefore, evaluated the relationship between trans fatty acid content in erythrocytes—a biomarker for trans fat intake—and risk of CHD in 166 incident cases of CHD and 327 matched controls identified from the Nurses' Health Study.
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