The Reynolds Risk Score: improved accuracy for cardiovascular risk prediction in women?
Nanette K Wenger
Correspondence Division of Cardiology, Emory University School of Medicine, 49 Jesse Hill Jr Drive, Atlanta, GA 30303, USA
Email nwenger@emory.edu
This article has no abstract so we have provided the first paragraph of the full text.
Traditionally, the FRS1 has been used to assess cardiovascular risk, as incorporated in the US National Cholesterol Education Program ATP III 2001 lipid management recommendations.2 The emphasis of the FRS on 10-year risk has, however, been postulated to underestimate the risk in women given their 10-year delay in the onset of clinical coronary disease compared with men; many consider this contributory to suboptimal cardiovascular risk assessment and intervention in women. A low FRS does not guarantee low lifetime cardiovascular risk, and subclinical coronary atherosclerosis has been documented among women with a family history of premature atherosclerosis and a low FRS.3 As with the FRS, it is likely that cardiovascular risk in nonwhite women is overestimated or underestimated by the Reynolds Risk Score.
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