Research Highlights

Nature Clinical Practice Cardiovascular Medicine (2007) 4, 348
doi:10.1038/ncpcardio0891  

Drug-eluting stents not associated with worse long-term outcome than bare-metal stents

This article has no abstract so we have provided the first paragraph of the full text.

The use of drug-eluting stents (DESs) in percutaneous coronary intervention reduces the occurrence of restenosis and, consequently, the need for repeat revascularization. The initial randomized studies of DESs focused on their efficacy at reducing restenosis, and were, therefore, inadequately powered to assess differences in the occurrence of less frequent events such as death, myocardial infarction and stent thrombosis. Recent studies have indicated that DESs might be associated with a worse long-term prognosis than bare-metal stents (BMSs). In response to this concern, three research groups have carried out pooled analyses to examine the long-term safety of DESs, as compared with BMSs.

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