The pathophysiology of heart failure with a normal ejection fraction, and hypertension
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Population-based studies report that the majority of elderly patients with heart failure have a normal ejection fraction (HF-NEF) and a history of hypertension. Left ventricular diastolic dysfunction, with normal or reduced left ventricular diastolic chamber size despite increased filling pressures, is usually suggested as the cause. Maurer et al. investigated the influence of these and other factors using data from the population-based Cardiovascular Health Study.
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