Research Highlights

Nature Clinical Practice Cardiovascular Medicine (2007) 4, 176-177
doi:10.1038/ncpcardio0809  

Long-term clopidogrel therapy improves outcomes after drug-eluting stent placement

This article has no abstract so we have provided the first paragraph of the full text.

Patients who receive coronary stents exhibit reduced rates of thrombosis if they receive antiplatelet therapy with thienopyridines, such as clopidogrel, following implantation. FDA-approved indications currently recommend that patients who undergo percutaneous intervention with drug-eluting stents (DESs) should be treated with clopidogrel for 3–6 months; however, evidence indicates that they might be at risk of late-stent thrombosis after discontinuing the drug. In an observational study, Eisenstein et al. have investigated the association between long-term clopidogrel use, and death and myocardial infarction (MI), after DES or bare metal stent (BMS) placement.

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