How important is screening angiography for CAS in diabetic patients awaiting transplant? A nephrologist's view
Jonathan A Winston
Correspondence Division of Nephrology, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1243, New York, NY 10029, USA
Email jonathan.winston@mssm.edu
This article has no abstract so we have provided the first paragraph of the full text.
Diabetes mellitus, an important risk factor for atherosclerosis and cardiovascular disease, has fueled the annual growth of the end-stage renal disease (ESRD) population, accounting for 44% of all incident cases of ESRD and 60% of cases between the ages of 60 and 74 years.1 Cardiovascular disease is the most important cause of death in ESRD, with at least one third of ESRD deaths attributable to ischemic heart disease. The cardiovascular disease risk extends to at least 8 million people in the US who have glomerular filtration rates below 60 ml/min/1.73m2. In addition, diabetes increases the risk of developing CKD by 5-fold to 12-fold. These associations between diabetes, CAD and CKD largely explain why cardiovascular disease has reached epidemic proportions in patients with CKD.
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