Research Highlights

Nature Clinical Practice Cardiovascular Medicine (2007) 4, 639
doi:10.1038/ncpcardio1018  

Benefits of implantable cardioverter-defibrillators maintained in clinical setting

This article has no abstract so we have provided the first paragraph of the full text.

Patients with left ventricular systolic dysfunction are at risk of ventricular arrhythmias and sudden cardiac death. Meta-analyses of randomized controlled trials (RCTs) have demonstrated that, in these patients, implantable cardioverter-defibrillators (ICDs) reduce mortality by 26% and sudden cardiac death by 57%. Some cardiologists, however, question whether the benefits of ICDs seen in clinical trials extend to clinical practice, where physicians who perform implantation procedures might not have the same level of experience.

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