Table of contents

December 2007 Volume 4 No 12

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Editorial

Meta-analysis of small trials: proceed with caution

Michael E Farkouh and Valentin Fuster

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doi:10.1038/ncpcardio1064 | Full Text | PDF (87K)

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Viewpoint

Spontaneous coronary artery dissection: where is the tear?

Paolo Angelini

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The Case Study by Satoda and colleagues, published in this issue of Nature Clinical Practice Cardiovascular Medicine, provides Paolo Angelini with an intriguing introduction to his Viewpoint on spontaneous coronary artery dissection (SCAD). Dr Angelini discusses our current understanding of this condition, and highlights recent progress in refining the diagnosis and definition of SCAD, made possible by new imaging modalities.

doi:10.1038/ncpcardio1039 | Full Text | PDF (163K)

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Research Highlights

Early statin therapy beneficial for familial hypercholesterolemia

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doi:10.1038/ncpcardio1015 | Full Text | PDF (84K)

Interleukin 1 receptor family member ST2 has prognostic value in dyspnea

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doi:10.1038/ncpcardio1016 | Full Text | PDF (84K)

Interactions between anti-thrombotic drugs increase the risk of gastrointestinal bleeding

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doi:10.1038/ncpcardio1017 | Full Text | PDF (89K)

Benefits of implantable cardioverter-defibrillators maintained in clinical setting

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doi:10.1038/ncpcardio1018 | Full Text | PDF (84K)

Heart failure with preserved left ventricular systolic function: is it being overlooked?

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doi:10.1038/ncpcardio1019 | Full Text | PDF (90K)

Optical coherence tomography permits detailed characterization of vulnerable plaques

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doi:10.1038/ncpcardio1020 | Full Text | PDF (84K)

Autopsy study demonstrates clustering of vulnerable coronary plaques

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doi:10.1038/ncpcardio1021 | Full Text | PDF (84K)

18FDG-PET imaging of atherosclerotic plaque inflammation

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doi:10.1038/ncpcardio1022 | Full Text | PDF (90K)

Benefits of fondaparinux over enoxaparin in patients with renal dysfunction: OASIS 5 data

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doi:10.1038/ncpcardio1023 | Full Text | PDF (84K)

Dronedarone successfully maintains sinus rhythm in patients with atrial fibrillation

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doi:10.1038/ncpcardio1024 | Full Text | PDF (89K)

OP CABG surgery: good short-term outcomes, increased risk for subsequent revascularization

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doi:10.1038/ncpcardio1025 | Full Text | PDF (82K)

Premature parental CVD associated with increased risk of vascular calcification

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doi:10.1038/ncpcardio1026 | Full Text | PDF (88K)

Endothelial progenitor cells predict mortality in patients with congestive heart failure

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doi:10.1038/ncpcardio1027 | Full Text | PDF (83K)

Diabetes increases risk of mortality in patients with acute coronary syndromes

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doi:10.1038/ncpcardio1028 | Full Text | PDF (83K)

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Practice Points

Can tissue Doppler imaging detect myocardial viability in patients with left ventricular dysfunction?

Jeroen J Bax and Don Poldermans

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doi:10.1038/ncpcardio1031 | Full Text | PDF (167K)

Total erythrocyte membrane cholesterol: a marker of plaque instability?

Aloke V Finn and Herman K Gold

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doi:10.1038/ncpcardio0986 | Full Text | PDF (165K)

Is rosiglitazone associated with increased risk for cardiovascular events?

Markolf Hanefeld

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doi:10.1038/ncpcardio1030 | Full Text | PDF (167K)

Long-term outcomes and cost-effectiveness of screening for abdominal aortic aneurysm

Jeffrey W Olin

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doi:10.1038/ncpcardio1004 | Full Text | PDF (162K)

Does NT-proBNP testing reduce costs and improve accuracy in the diagnosis of heart failure?

A Mark Richards

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doi:10.1038/ncpcardio1014 | Full Text | PDF (168K)

Does estrogen therapy reduce coronary artery calcification in postmenopausal women?

John C Stevenson

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doi:10.1038/ncpcardio1011 | Full Text | PDF (166K)

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Reviews

Patient-centered prevention strategies for cardiovascular disease, cancer and diabetes

Kathryn A Taubert, Nathaniel G Clark and Robert A Smith

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In this Review, Kathryn Taubert, Nathaniel Clark and Robert Smith explore the common features and risks of cardiovascular disease, cancer and diabetes—disease which together are responsible for more than 25 million deaths in the world each year. They examine the important role of cardiology health-care providers with regards to risks for other chronic conditions and occult disease.

doi:10.1038/ncpcardio1029 | Full Text | PDF (561K)

Risk stratification of sudden cardiac death in hypertrophic cardiomyopathy

Marc A Miller, J Anthony Gomes and Valentin Fuster

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Identifying high-risk individuals with hypertrophic cardiomyopathy is paramount as the first clinical expression is often the most devastating—sudden cardiac death. Miller and colleagues review the established or 'major' risk factors used to identify high-risk patients, and discuss the possible and future risk factors for hypertrophic cardiomyopathy-related sudden cardiac death.

doi:10.1038/ncpcardio1057 | Full Text | PDF (363K)

Continuing Medical Education

Technology Insight: magnetic resonance angiography for the evaluation of patients with peripheral artery disease

Santo Dellegrottaglie, Javier Sanz, Frank Macaluso, Andrew J Einstein, Subha Raman, Orlando P Simonetti and Sanjay Rajagopalan

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In this instructive Therapy Insight, Dellegrottaglie et al. examine the role of magnetic resonance angiography (MRA) in the initial diagnosis and subsequent management of patients with peripheral arterial disease, comparing this technique with other diagnostic modalities. They explain, in simple terms, current MRA methodologies and ongoing technical improvements as they apply to the evaluation of lower extremity vessels.

doi:10.1038/ncpcardio1035 | Full Text | PDF (609K)

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Case Study

Continuing Medical Education

Acute myocardial infarction caused by spontaneous postpartum coronary artery dissection

Masahiko Satoda, Kensuke Takagi, Michitaka Uesugi, Itsuro Morishima, Hiroaki Mukawa, Hideyuki Tsuboi and Takahito Sone

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In this month's Case Study, Satoda et al. describe a patient who presented with an acute myocardial infarction 5 weeks after giving birth. Angiography revealed a severe diffuse lesion of the left anterior descending artery, which was later confirmed to be a spiral dissection. The lesion resolved after two months of medical therapy, and the patient recovered well.

doi:10.1038/ncpcardio1055 | Full Text | PDF (344K)

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