Can tissue Doppler echocardiography detect subclinical myocardial dysfunction in patients with diabetes?
Mario J Garcia
Correspondence Cardiovascular Institute, Mount Sinai School of Medicine, Box 1234, One Gustave L Levy Place, New York, NY 10029, USA
Email mario.garcia@mssm.edu
This article has no abstract so we have provided the first paragraph of the full text.
The incidence of diabetes mellitus has reached epidemic proportions, affecting more than 170 million people worldwide. Cardiovascular disease is the leading cause of death among these individuals.1 Poor glycemic control in patients with diabetes has been associated with microvascular disease, which can provoke episodes of ischemia and can cause impaired LV relaxation and increased myocardial stiffness. Advanced glycation end products, which are formed faster in people with diabetes than in healthy individuals, are linked to the development of diabetic cardiomyopathy. Furthermore, several large epidemiological studies have identified that diabetes is a major risk factor for the development of HF.2, 3
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