Research Highlights

Nature Clinical Practice Cardiovascular Medicine (2007) 4, 525
doi:10.1038/ncpcardio0974  

Use of ICDs for primary prevention following acute MI

This article has no abstract so we have provided the first paragraph of the full text.

In MADIT II, defibrillator implantation after myocardial infarction (MI) reduced sudden cardiac death by 67% in patients with a left ventricular ejection fraction (LVEF) of 30% or less. The FDA consequently approved implantable cardioverter-defibrillator (ICD) use in patients meeting the entry criteria for this trial, but there is still some controversy over the cost-effectiveness of ICDs in this patient group, and over the LVEF cutoff used to determine whether a device should be implanted.

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